Isaac Yellan

A picture I took of Van Gogh's portrait at the Chicago Art Institute. Basically what I look like +/- an ear.

I am a recent PhD graduate from the Department of Molecular Genetics at the University of Toronto. I am a member of the lab of Dr. Timothy R. Hughes, where I study the impact of selfish genetic elements on the evolution of genome regulation, particularly transcription factors.

My research has led me through the murky genomic waters of many a fish, particularly the majestic coelacanth, which led to some coverage of my work in some notable (and less than noble!) outlets.

More generally, I have extensive experience in studying molecular evolution and applying computational tools to understand comparative genomic evolution, and along the way gained expertise in integrating large, complex datasets and datatypes.

You can contact me at: isaac[dot]yellan[at]mail[dot]utoronto[dot]ca, or by checking out my various internet presences, linked above.

selected publications

Genetics

Reconstruction of Full-Length LINE-1 Progenitors from Ancestral Genomes

Laura F Campitelli, Isaac Yellan, Mihai Albu, and 4 more authors

Genetics, Jul 2022

Bib HTML

@article{campitelliReconstructionFulllengthLINE12022,
  ids = {campitelliReconstructionFulllengthLINE12022a},
  title = {Reconstruction of Full-Length {{LINE-1}} Progenitors from Ancestral Genomes},
  author = {Campitelli, Laura F and Yellan, Isaac and Albu, Mihai and Barazandeh, Marjan and Patel, Zain M and Blanchette, Mathieu and Hughes, Timothy R},
  editor = {Barbash, D},
  year = {2022},
  month = jul,
  journal = {Genetics},
  volume = {221},
  number = {3},
  issn = {1943-2631},
  doi = {10.1093/genetics/iyac074},
  urldate = {2022-11-16},
  langid = {english},
  file = {/Users/isaacyellan/OneDrive - University of Toronto/zotero_files/Campitelli et al_2022_Genetics.pdf;/Users/isaacyellan/OneDrive - University of Toronto/zotero_files/supp_figs.pdf},
}

MBE

Diverse Eukaryotic CGG-Binding Proteins Produced by Independent Domestications of hAT Transposons

Isaac Yellan, Ally W H Yang, and Timothy R Hughes

Molecular Biology and Evolution, May 2021

Bib HTML

@article{yellanDiverseEukaryoticCGGBinding2021,
  title = {Diverse {{Eukaryotic CGG-Binding Proteins Produced}} by {{Independent Domestications}} of {{hAT Transposons}}},
  author = {Yellan, Isaac and Yang, Ally W H and Hughes, Timothy R},
  editor = {Nowick, Katja},
  year = {2021},
  month = may,
  journal = {Molecular Biology and Evolution},
  volume = {38},
  number = {5},
  pages = {2070--2075},
  issn = {1537-1719},
  doi = {10.1093/molbev/msab007},
  urldate = {2022-11-16},
  langid = {english},
  file = {/Users/isaacyellan/OneDrive - University of Toronto/zotero_files/Yellan et al_2021_Molecular Biology and Evolution8.pdf;/Users/isaacyellan/Zotero/storage/ZAPZSFLY/TableS1.xls;/Users/isaacyellan/Zotero/storage/C5XRFVLE/6129264.html},
}